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Nitrosigine® From Nutrition21

Accepted and used by athletes, bodybuilders, and fitness enthusiasts as a stimulant-free and industry standout pre-workout muscle pump booster.

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Nitrosigine® From Nutrition21

Accepted and used by athletes, bodybuilders, and fitness enthusiasts as a stimulant-free and industry standout pre-workout muscle pump booster.

Vegan Icon Status
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Nitrosigine® is a non-stimulant, cutting-edge, patented complex consisting of bonded arginine silicate, meticulously designed to unlock peak sports performance. It combines two key components: arginine, an amino acid that plays a pivotal role in expanding blood vessels and improving blood flow, and silicate, naturally found in various plant-based foods. Backed by an extensive body of research, Nitrosigine® is proven to boost nitric oxide (NO) production, enhancing blood flow, concentration, and energy levels. It promotes blood vessel dilation for heightened blood flow during physical activities, contributing to optimal sports performance.

Primary Benefits

Nitrosigine® is added to sports nutrition supplements because it caters to individuals seeking enhanced exercise and athletic performance.  It also delivers improved blood flow, producing better muscle pumps during workouts. It may also reduce muscle damage, resulting in faster recovery with better mental focus, making it valuable for athletes and fitness enthusiasts. Its ability to support heart health and overall well-being further extends its appeal.  

Food For Thought

Nitrosigine®is backed by 30 studies and confirmed by the US FDA as Generally Recognized as Safe (GRAS). It’s also a trusted non-stimulant ingredient available in various forms like capsules, powder, and ready-to-drink beverages, making it a safe and versatile choice for athletes and fitness enthusiasts.

Bottom Line

It’s a stand-out non-stimulant ingredient found in many pre-workout products.  Nitrosigine® is known for its ability to promote better pumps, improve workout performance, and enhance recovery. Nitrosigine® is patented and with more than 30 scientific studies that document its claims. It has been awarded GRAS (generally recognized as safe) status. Over thirty scientific studies back up these well-documented benefits. Lastly, Nitrosigine® is wildly popular and extensively used in numerous products with obvious industry acceptance. 

Product Highlights

  • Promote Increased NO Levels
  • Accelerate Recovery From Exercise
  • Boosts Muscle Pump
  • Improves Focus & Energy

We had to share this again! Nitrosigine® is a remarkable supplement known for elevating arginine levels in the bloodstream for up to six hours. To achieve improved blood flow, only 1.5 grams of Nitrosigine® is required, equivalent to the effects of 8 grams of Citrulline. Within 30 minutes of ingestion, a single dose of Nitrosigine® can rapidly increase arginine levels in the blood, maintaining this effect for a substantial six-hour duration. This sustained presence of Nitrosigine® is beneficial for enhancing exercise performance but also aids in muscle recovery post-exercise, making it a valuable addition to any fitness regimen.

Most pre-workouts contain stimulants like caffeine. Be aware that the caffeine intake at 1 dose of 750 mg may be safe, at 2 doses the caffeine intake may be excessive. We strongly urge you to evaluate the effectiveness of the product at a single dose of 750 mg and more importantly make sure the stimulant dose isn’t excessive.


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Content on GenMag™ is for informational purposes only and is not intended to diagnose, treat, prevent, or cure any physical or medical condition. While our articles may cover a variety of topics, including specialty ingredients that may potentially support various health goals, they are not a substitute for a balanced diet and healthy lifestyle habits. We strongly recommend consulting a healthcare professional before taking any health supplement or starting an exercise program, especially if you have a pre-existing medical condition or take medication. Certain supplements may interact with medications and pose health risks.

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